The Case Book of Sherlock Holmes contains twelve stories written about the legendary consulting detective by his creator Arthur Conan Doyle. Like all the other Sherlock Holmes adventures, these stories were originally published in the Strand Magazine, in this case between October 1921 and April 1927. What sets the stories collected in the Case Book of Sherlock Holmes from all other anthologies is that that they represent the winding down of a literary sensation. These are the last original mysteries of Holmes to be published in the Strand and this is the last collection of original stories penned by Doyle.